Deeper Understanding of Osteosarcoma Biology Explains Challenges With Immunotherapy
Pharma & biotech2020-03-05
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Multiple immune-infiltrate features in the immune-genomic landscape of osteosarcoma, such as poor tumor infiltration by immune cells, low T-cell activity, a lack of immune-stimulating neoantigens, and immune-suppressing pathways, contribute to the limited clinical activity associated with checkpoint inhibitors in this disease, according to results of a study published in Nature Communications.
Source: OncLive
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