Whitehawk Therapeutics to Highlight its Next-Generation ADC Portfolio at the American Association for Cancer Research (AACR) Annual Meeting 2026
Whitehawk Therapeutics to Highlight its Next-Generation ADC Portfolio at the American Association for Cancer Research (AACR) Annual Meeting 2026 |
| [17-March-2026] |
MORRISTOWN, N.J., March 17, 2026 /PRNewswire/ -- Whitehawk Therapeutics, Inc. (Nasdaq: WHWK), a clinical-stage oncology therapeutics company applying advanced technologies to established tumor biology to efficiently deliver improved antibody drug conjugate (ADC) cancer treatments, today announced it will present three preclinical abstracts, including an oral minisymposium and two posters, highlighting its next-generation antibody-drug conjugate (ADC) portfolio at the American Association for Cancer Research (AACR) Annual Meeting 2026, taking place April 17–22, 2026, in San Diego, CA. "For the first time, we will present comprehensive preclinical proof-of-concept for our three ADC programs, HWK-007, HWK-016 and HWK-206," said David Dornan, PhD, Chief Scientific Officer of Whitehawk Therapeutics. "These data will highlight the optimized ADC design features aimed at delivering a differentiated ADC profile with the goal of improving outcomes for cancer patients." Whitehawk's comprehensive preclinical abstracts demonstrate a potential best-in-class therapeutic index among next-generation TOP1i-based ADCs. These data showed high potency with tumor regressions in xenograft studies at low single-digit mg/kg doses, and in non-human primate studies, Whitehawk's ADCs demonstrated a high tolerability with a highest non-severely toxic dose (HNSTD) of 60 mg/kg. Underpinning these results is one of the lowest reported free payload in circulation, driven by Whitehawk's proprietary "carbon-bridge cysteine repairing" linker-payload. Presentation details: HWK-016 – MUC16-Targeted ADC (Minisymposium Oral Presentation) HWK-007 – PTK7-Targeted ADC (Poster Presentation) HWK-206 – SEZ6-Targeted ADC (Poster Presentation) These abstracts are currently available on the AACR 2026 meeting website, and the presentation and posters will be accessible on the Presentations page of the Investors & News section of the Company's website at www.whitehawktx.com. About Whitehawk Therapeutics Forward Looking Statements Additional risks and uncertainties that could cause actual outcomes and results to differ materially from those contemplated by the forward-looking statements are included in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2025, including under the caption "Item 1A. Risk Factors," and in Whitehawk's subsequent Quarterly Reports on Form 10-Q, and elsewhere in Whitehawk's reports and other documents that Whitehawk has filed, or will file, with the SEC from time to time and available at www.sec.gov. All forward-looking statements in this press release are current only as of the date hereof and, except as required by applicable law, Whitehawk undertakes no obligation to revise or update any forward-looking statement, or to make any other forward-looking statements, whether as a result of new information, future events or otherwise. All forward-looking statements are qualified in their entirety by this cautionary statement. This cautionary statement is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Contact:
SOURCE Whitehawk Therapeutics, Inc. | ||
Company Codes: NASDAQ-NMS:WHWK |
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